Therapy optimisation trial to improve the treatment of liver cancer  

Liver cancer is rare in children and adolescents and is usually treated with surgery and chemotherapy. The chances of recovery are between 50 and 100 per cent, depending on the characteristics of the disease, but the intensive chemotherapy can lead to severe, long-term side effects such as hearing loss, heart problems and secondary cancers.  

Aim of the study

The PHITT trial aims to find better treatment strategies to improve patients’ chances of recovery and thus quality of life. The collected data will be analysed in order to determine the side effects of the treatment and the biological aspects of the cancer. Furthermore, it will be used to optimise existing surgical procedures for removing liver tumours and contribute to a better understanding of how the body deals with common treatment.

Implementing organisation

Swiss Paediatric Oncology Group (SPOG)